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56-Years Old Patient Undergoes Western India’s First Faecal Transplants

News - 56-Years Old Patient Undergoes Western India’s First Faecal Transplants



 

Fortis Hospital, Mulund, conducts Western India’s First Faecal Transplant

A 56- year old patient who developed severe bacterial infection of the intestine underwent faecal transplant at Fprtis, Hospital, Mulund. The procedure was performed by Dr. N . Arulvanan, General and Laprascopic Surgeon, Fortis Hospital, Mulund, under the guidance of Dr Kirti Sabnis, Infectious Disease Physician. This lesser known treatment was carried out for the first time in western India to treat a severe condition known as “Clostridium Difficile Colitis’, which causes inflammation and swelling of the large intestine. Unchecked us eof antibiotics kills good bacteris in the intestine, causing the disease.

The patient was initially admitted at Fortis Hopital, Mulundd, after being diagonised with Ischemic Heart Disease for which he underwent a Coronary Artery Bypass Grafting surgery. He soond developed pain in the abdomen along with loose motion, accompanied by fever. His blood pressure dropped and he was also diagonised with reduced kidney function. Further Investigations revealed the bacterial  infection as  the cause  of the ailment.

He was then advised the stool transplant known as Faecal Microbiota  Transplant by Dr Kirti Sabnis. The transplant involves introduction of healthy bacteris from a healthy donor  to the recipient. This is carried  out therough infusion of stool by enema, tube or orally in the form of slurry or capsule. As part of further treatment, the patient also underwent a procedure to remove the  severely affected  part of the intestine. It was a high  risk procedure since the patient was on ventilator support for his kidneys.

The first successful stool transplant in India was carried out at Fortis Memorial Research Institute, Gurugram in 2014 for a 44 year old male suffering from severe Ulcerative Colitis for over a decade. He underwent three sessions of stool transplant through colonoscopy from a 34 year old healthy donor. There was marked clinical improvement and he continues to be in remission at 18 months follow up without corticosteroids or azathioprine.

Dr Avnish Seth, Director Gastroenterology & Hepatobiliary Sciences at FMRI, Gurugram, has pioneered the technique of stool transplant in the country. A study on Faecal Microbiota Transplant (FMT) in patients with severe Ulcerative Colitis showed remarkable results with 6 out of 10 achieving and maintaining remission. 

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